What is Hodgkin lymphoma?

Lymphoma is a cancer of the lymphatic system.

The body is made up of cells that need to be replaced as they age or are damaged. This happens through cell division, which is when a cell divides and makes new copies of itself.

Normally, cell division is carefully controlled. But sometimes this process can get out of control. Too many cells may be made and a cancer, such as lymphoma, can develop.

In lymphoma, blood cells called lymphocytes become abnormal. These are the lymphoma cells. Usually the body’s immune system destroys abnormal cells. But lymphoma cells are often able to avoid the immune system. This means they can keep dividing and grow out of control. Over time, there are enough lymphoma cells to form a lump. The most common place for this to happen is in the lymph nodes. But lymphoma can start growing in other parts of the body.

Lymphocytes travel around the body. This means that lymphoma can spread from where it first started. It can spread through the lymphatic system from lymph nodes in one part of the body to lymph nodes elsewhere. Lymphoma cells can also travel in the bloodstream to organs such as the bone marrow, liver or lungs. The cells may then keep dividing to form a new area of lymphoma.

What is Hodgkin lymphoma?

There are many types of lymphoma. Different types develop and are treated in different ways. The two main sub-types are Hodgkin lymphoma and non-Hodgkin lymphoma. A doctor can only find out your lymphoma type by collecting some lymphoma cells and examining them under a microscope.

About 1 in 5 (20%) of all diagnosed lymphomas are Hodgkin lymphoma. Around 1,700 people are diagnosed with Hodgkin lymphoma in the UK each year. It can affect people at any age. However, it is more common in people who are 20 to 34 years old or over 70 years old.

Hodgkin lymphoma can begin in almost any part of the body. But it usually starts in the lymph nodes. The most common area is the lymph nodes in the neck. Often several areas of lymph nodes around the body are affected. Sometimes organs such as the spleen, bone marrow or liver are affected too.

An image of Dr Marcus, a lymphoma specialist.

Diagnosing lymphoma

In this cancer information video, Dr Robert Marcus explains what lymphoma is and how it is diagnosed. Linda, who had non-Hodgkin lymphoma, talks about how she felt when she was told of her diagnosis.

About our cancer information videos

Diagnosing lymphoma

In this cancer information video, Dr Robert Marcus explains what lymphoma is and how it is diagnosed. Linda, who had non-Hodgkin lymphoma, talks about how she felt when she was told of her diagnosis.

About our cancer information videos

Back to Understanding Hodgkin lymphoma

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