Treatment for testicular cancer
After surgery to remove the testicle (orchidectomy), further treatment will depend on the stage and type of testicular cancer you have.
About treatment for testicular cancer
The three main treatments for testicular cancer are:
- surgery to remove a testicle (orchidectomy)
- chemotherapy to reduce the risk of the cancer coming back, or treat testicular cancer that has spread, or comes back after treatment
- radiotherapy
If testicular cancer has spread to the lymph nodes at the back of the tummy (abdomen), you may need surgery to remove the retroperitoneal lymph nodes.
After surgery to diagnose the cancer and remove the testicle your doctor will talk to you about surveillance. Surveillance is the option of monitoring you regularly in clinic. Or they may suggest you have further treatment.
Further treatment will depend on:
- the stage of the cancer and the risk of it coming back
- whether it is a non-seminoma or seminoma (see below).
Doctors also look at other factors such as, the size of the tumour and the levels of tumour markers, if present.
We understand that having treatment can be a difficult time for people. We're here to support you. If you want to talk, you can:
- Call the Macmillan Support Line on 0808 808 00 00.
- Chat to our specialists online.
- Visit our testicular cancer forum to talk with people who have been affected by testicular cancer, share your experience, and ask an expert your questions.
See also
Treating stage 1 testicular cancer
Stage 1 testicular cancer is cancer that has not spread outside the testicle. Surgery to remove the testicle (orchidectomy) may be the only treatment you need.
After orchidectomy, your doctor will talk to you about surveillance (monitoring) if the risk of the cancer coming back is low.
Your doctor may also offer you adjuvant chemotherapy treatment to reduce the risk of the cancer coming back.
Your doctor will explain why they have suggested adjuvant treatment. Your doctor and nurse will talk you through the benefits and disadvantages of each option and what might be best in your situation.
You may decide not to have treatment, and to have surveillance instead. You may want to avoid treatment that might not be necessary. Sometimes, if you have option of surveillance you may decide to have chemotherapy instead.
Talk about the treatments with your doctor. Make sure you have enough information to help you make your decision.
See also
Seminoma stage 1
If you have a stage 1 seminoma, your doctor may suggest you have surveillance (monitoring). This is if there is a low risk of the cancer coming back. You usually need to have regular clinic appointments for several years.
They may also offer you a single dose of adjuvant chemotherapy, with a drug called carboplatin.
Your doctors decide if you will benefit from adjuvant treatment based on:
- the size of the tumour
- how it looks under a microscope
- the tumour marker levels (if present).
Non-seminoma stage 1
If you have a stage 1 non-seminoma, your doctor may suggest surveillance if there is a low risk of the cancer coming back. After a few years, if scans show no signs of the cancer coming back, you may only need regular blood tests.
They may also offer the option of adjuvant chemotherapy with bleomycin, etoposide and cisplatin (BEP). You may have 1 or 2 sessions. This will depend on:
- how the cancer looks under a microscope
- if it has spread to nearby blood vessels
- the size of the tumour
- the tumour marker levels (if present).
Rarely, your doctor may suggest further surgery to remove the lymph nodes at the back of the tummy (retroperitoneal lymph nodes).
See also
Treating stages 2 to 4
If the cancer has spread outside your testicle, you have chemotherapy or occasionally radiotherapy, after having an orchidectomy. This will depend on the type of cancer.
Treatment can also depend on the stage of the cancer. Your doctors will talk to you about the treatment they think is best for you.
Seminoma
If you have a seminoma that has spread, your doctor may offer treatment with radiotherapy. Or they may offer you 3 or 4 courses of chemotherapy. Your doctor will talk with you about the treatment they think is best for you.
Non-seminoma
If you have a non-seminoma that has spread, you may need 3 or 4 sessions of chemotherapy. Or you may need more intensive chemotherapy. This will depend on the stage of cancer, certain risk factors and how you respond to standard chemotherapy.
If you have non-seminoma you may need surgery after chemotherapy to remove the retroperitoneal lymph nodes, if they are enlarged.
If testicular cancer comes back
If testicular cancer comes back, treatment can still usually cure it. This is even if the cancer has spread to other parts of the body.
Effects of treatment on sex life and fertility
Treatments for testicular cancer can sometimes affect your ability to make someone pregnant (fertility). Doctors usually advise you to store your sperm (sperm banking) after, or sometimes before an orchidectomy.
Treatments do not affect your ability to have sex. But the emotional effects of your diagnosis and treatment side effects may reduce your sex drive for a while. There is different support available if you are having difficulties with your sex life.
We have more information about testicular cancer your sex life and fertility.
About our information
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References
Below is a sample of the sources used in our testicular cancer information. If you would like more information about the sources we use, please contact us at cancerinformationteam@macmillan.org.uk
European Association of Urology. Guidelines on Cancer. 2016. Available from: www.baus.org.uk/_userfiles/pages/files/professionals/sections/oncology/EAU2015-Testicular-Cancer.pdf (accessed August 2018)
European Society for Medical Oncology, eUpdate. Testicular Seminoma and Non-Seminoma Treatment Recommendations. June 2017. Available from: www.esmo.org/Guidelines/Genitourinary-Cancers/Testicular-Seminoma-and-Non-Seminoma/eUpdate-Treatment-Recommendation (accessed August 2018).
Scottish Intercollegiate Guidelines Network, Management of adult testicular germ cell tumours. Available from: www.sign.ac.uk/sign-124-management-of-adult-testicular-germ-cell-tumours.html (accessed August 2018).
UpToDate. Clinical manifestations, diagnosis, and staging of testicular germ cell tumors. January 2018. Available from: www.uptodate.com/contents/clinical-manifestations-diagnosis-and-staging-of-testicular-germ-cell-tumors (accessed August 2018).
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Reviewers
This information has been written, revised and edited by Macmillan Cancer Support’s Cancer Information Development team. It has been reviewed by expert medical and health professionals and people living with cancer. It has been approved by Senior Medical Editor, Dr Jim Barber, Consultant Clinical Oncologist.
Our cancer information has been awarded the PIF TICK. Created by the Patient Information Forum, this quality mark shows we meet PIF’s 10 criteria for trustworthy health information.
Content under review
The language we use
We want everyone affected by cancer to feel our information is written for them.
We try to make sure our information is as clear as possible. We use plain English, avoid jargon, explain any medical words, use illustrations to explain text, and make sure important points are highlighted clearly.
We use gender-inclusive language and talk to our readers as ‘you’ so that everyone feels included. Where clinically necessary we use the terms ‘men’ and ‘women’ or ‘male’ and ‘female’. For example, we do so when talking about parts of the body or mentioning statistics or research about who is affected. Our aims are for our information to be as clear and relevant as possible for everyone.
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