Prehabilitation resources for healthcare professionals

Prehabilitation for people with cancer: Clinical and implementation guidelines

Developed in collaboration with the NIHR Southampton Biomedical Research Centre, the Centre for Perioperative Care, the Royal College of Anaesthetists, the NIHR Cancer Nutrition Collaborative and the World Cancer Research Fund.

These updated 2025 guidelines build on the original guidance published in 2019. These guidelines provide detailed, evidence-based recommendations for designing and delivering prehabilitation services for people living with cancer.

They aim to support widespread adoption of prehabilitation to improve patient preparation, recovery, experience of care and sense of control. They also include practical information to help healthcare provider organisations develop services tailored to communities they serve.

Use these guidelines to:

  • Support clinical decision-making
  • Tailor services to local populations
  • Prepare for future journal publications expanding on key topics

Read the Clinical and Implementation Guidelines (PDF)

Coming in 2026:

We will be linking to seven peer-reviewed journal articles covering implementation, behaviour change, nutrition, psychology, health economics, and more.

Prehabilitation principles and guidance

We have developed our principles and guidance for prehabilitation in partnership with the Royal College of Anaesthetists, the National Institute for Health Research Cancer, and Nutrition Collaboration.

These resources will help you to:

  • include prehabilitation into cancer pathways.
  • inform service provision and development
  • Advance personalised cancer care

Digital learning resources - videos, podcasts and webinars

Learn from healthcare professionals, researchers and people living with cancer about the value of prehabilitation.

Prehabilitation video series

In partnership with Bristol Myers Squibb and people living with cancer, we have created six short videos to help you introduce prehabilitation to your patients. Topics include:

  • What is prehabilitation?
  • Physical activity
  • Eating well
  • Mental wellbeing
  • Alcohol moderation
  • Stopping smoking 

View the prehabilitation videos.

Prehabilitation summit videos

Access recordings from the first joint NHSE and Macmillan Prehabilitation Summit to deepen your understanding and share insights with your team. These sessions highlight national progress, emerging evidence, and practical strategies for implementing prehabilitation across services. 

Watch: Summit Introduction 


Other videos from the summit

Podcasts and webinars

We spoke to professionals and people living with cancer to understand their experiences of prehabilitation. You can hear what they told us in our series of podcasts.

Physical activity resources

We want everyone living with cancer to get the support and inspiration they need to be physically active, in a way that's right for them.

Physical activity can help people living with cancer:

  • manage their symptoms
  • improve their quality of life and clinical outcomes
  • prevent treatment side effects
  • reduce the risk of recurrence.

You can learn more about these benefits in our physical activity guidance. We have separate physical activity guidance for patients with metastatic bone disease.

We also have a service implementation guide and sports toolkit to help professionals develop or signpost patients to a physical activity service.

Please find below links to additional information around physical activity and exercise developed by the South East London Cancer Alliance for patients and those working with people with cancer.

The Centre for Perioperative care have developed patient resources to help people prepare for surgery or treatment. These highlight the importance of shared decision making when it comes to your treatment and achieving the best outcomes.

10 top tips for primary care

We've created our 10 top tips series to help primary care professionals support patients at every stage of the cancer pathway. The tips are designed to showcase best practice and offer practical advice for your role.

We have tips for prehabilitation, which include:

View all top tips

Join online specialist group

The Q Perioperative Care-Prehabilitation Special Interest Group (SIG) is hosted by Macmillan and the Centre for Perioperative Care (CPOC). This partnership brings together professionals, charities and Royal Colleges to share learning and improve care. .

The group focuses on supporting and optimising people’s physical and mental health before, during and after treatment for cancer and other long-term conditions.

Join the group.

Innovation in cancer care resources

We invest in programmes and services that help healthcare professionals deliver more personalised cancer care. Working in partnership with communities and the NHS, we fund pilot projects to improve experiences and outcomes for people living with cancer.

Our resources are informed by real-world learning and research and are designed to support your role in service development, clinical decision-making and quality improvement.

Research

These reports offer practical evidence to support service planning, workforce development and improved patient outcomes.

Find out more about our work

Clinical updates for healthcare professionals

Stay up to date with the latest developments in cancer care, with expert news, opinion and analysis. You'll also find blogs about our professionals and the fantastic work they do.

Read our latest blogs for healthcare professionals.

Read our prehabilitation resources for healthcare professionals.