About types of small bowel cancer

There are four main types of small bowel cancer. They are named after the cells where they develop.

For more information on other types of small bowel cancer, contact our cancer information nurses on the Macmillan Support Line on 0800 808 00 00.


These are the most common type of small bowel cancer. They start in the lining of the small bowel. They are usually in the duodenum.


Sarcomas develop in the supportive tissues of the body. There are different types of sarcoma. The most common is a gastrointestinal stromal tumour (GIST). A GIST can develop in any part of the small bowel.

Other types include leiomyosarcomas. These are usually in the muscle wall of the small bowel, usually in the ileum.

Neuroendocrine (carcinoid) tumours

Neuroendocrine tumours start from cells that make hormones inside the small bowel. They usually start in the ileum. Sometimes they are in the appendix.


Lymphomas start in the lymph tissue of the small bowel. The lymph tissue is part of the body’s immune system. Small bowel lymphomas are usually non-Hodgkin lymphomas (NHLs).

Small bowel lymphomas are most common in the jejunum or ileum.

Secondary cancer in the small bowel

Occasionally, a small bowel cancer may be a secondary cancer. This means it has spread from a cancer that started somewhere else in the body (primary cancer). The most common places for secondary cancers to spread from are the skin (melanoma), lung, breast and large bowel (colon).

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