CODOX-M chemotherapy is used to treat high-grade lymphomas, such as Burkitt lymphoma and some diffuse large B-cell lymphomas. It is best to read this information with our general information about chemotherapy and the type of cancer you have.
CODOX-M is named after the initials of the chemotherapy drugs used:
- C – cyclophosphamide and cytarabine
- O – vincristine, also known as oncovin
- DOX – doxorubicin
- M – methotrexate.
Some people will also have a targeted therapy drug called rituximab with each cycle. The combination is then called R-CODOX-M.
Sometimes, a chemotherapy treatment called IVAC is given between each cycle of CODOX-M. Your doctor, specialist nurse, or pharmacist will give you more information. They will also talk to you about the possible side effects before you agree (consent) to have treatment.