About treatment for oesophageal cancer

Oesophageal cancer can be treated with:

The treatments can be used alone or together.

Your treatment for oesophageal cancer depends on:

  • the type of oesophageal cancer you have
  • where the cancer is in the oesophagus – in the upper, middle or lower oesophagus
  • the stage and grade of the cancer
  • your general health and level of fitness
  • your personal choices.

You might have treatment to cure the cancer. If a cure is not possible, the aim of treatment is to control the cancer and help with the symptoms.

Your cancer doctor and specialist nurse will explain the treatments they think are best for you. They can help you make decisions about your treatment. If you do not understand something, it is important to ask them.

We understand that having treatment can be a difficult time for people. We're here to support you. If you want to talk, you can:

How treatment for oesophageal cancer is planned

After your test results, you and your doctor start to talk about your treatment. Your doctor usually meets with other specialists to get their opinions too.

Multidisciplinary team (MDT) meeting

A team of specialists meet to talk about the best treatment for you. They are called a multidisciplinary team (MDT).

The MDT reviews national treatment guidelines or the latest evidence for the type of cancer you have. If you have any treatment preferences, your doctor will tell them about this.

The MDT will usually include the following professionals:

  • a surgeon who specialises in oesophageal and stomach cancers
  • a medical oncologist – a doctor who uses chemotherapy and other anti-cancer drugs to treat people with cancer
  • a clinical oncologist – a doctor who uses radiotherapy, chemotherapy and other anti-cancer drugs to treat people with cancer
  • a gastroenterologist – a doctor who treats problems with the digestive system
  • clinical nurse specialist (CNS) – a nurse who gives information about cancer, and support during treatment
  • a dietitian – someone who gives information and advice about food and food supplements
  • a radiologist – a doctor who looks at scans and x-rays to diagnose problems
  • a pathologist – a doctor who looks at cells or body tissue under a microscope to diagnose cancer.

It may also include other healthcare professionals, including:

  • a palliative care doctor or nurse – someone who helps with symptom control
  • a physiotherapist – someone who gives advice about exercise and mobility
  • an occupational therapist – someone who gives information, support and aids to help people with tasks such as washing and dressing
  • a psychologist or counsellor – someone who can talk with you, and help you understand your feelings and find ways of coping with them.

After the MDT meeting, your cancer doctor or specialist nurse will talk to you about your treatment options. You can decide together on the best treatment plan for you.

Preparing for treatment

Maintaining your weight

After being diagnosed with oesophageal cancer, you may be referred to a dietitian. You may have difficulty eating and may have lost weight. A dietitian can:

  • give you support and advice on eating well
  • help you stop losing weight.

This helps you prepare for treatment.

It may help to try eating softer foods such as soup, or jelly and custard. These may be easier to swallow. You may also find that eating small, soft meals 4 to 5 times a day is easier than 2 to 3 bigger meals. Blending foods you like may help you eat more. If you cannot swallow anything, tell your healthcare team straight away.

We have more information about maintaining your weight.

Prehabilitation

Research suggests that making certain lifestyle changes before your treatment can help you cope better with side effects and improve your recovery.

Your healthcare team may suggest things you can do to improve your general health before treatment. This is sometimes called prehabilitation. It can help reduce the risk of complications such as blood clots. It can also help you to recover faster.

Prehabilitation can include:

Related video

Treating early-stage oesophageal cancer

The treatment you are offered will depend on your individual situation. The cancer multidisciplinary team will meet and discuss the treatment options available to you. Your doctor will talk to you more about these.

Endoscopic mucosal resection (EMR)

If you have very early stage oesophageal cancer, the cancer may be removed using an endoscope. This is called an endoscopic mucosal resection (EMR), or an endoscopic submucosal dissection (ESD). These can be offered if the tumour is very small and only affecting the inner layer of the oesophagus.

For most cancers that have not spread beyond the oesophagus and lymph nodes, doctors recommend combining different types of treatment. How these are combined depends on the type of oesophageal cancer.

Chemoradiation

Most people diagnosed with squamous cell cancer receive chemotherapy and radiotherapy. This is called chemoradiation. Some people may not need any further treatment. For others, chemoradiation or chemotherapy alone may be used to shrink a cancer so that it can then be removed with an operation.

If you are diagnosed with oesophageal adenocarcinoma, you will usually need an operation. Before this, you will generally be offered either chemoradiation or chemotherapy, which is given both before and after the operation.

Oesophagectomy

The main operation used to treat adenocarcinoma and squamous cell carcinoma in the oesophagus is called an oesophagectomy. This is where a surgeon removes all or part of your oesophagus. This is a major operation, and you need to be well enough to have it. If you are unable to have an oesophagectomy, you may be offered chemoradiation or radiotherapy on its own instead.

If you have had surgery, a pathologist will examine the tissue removed under a microscope. A pathologist is a doctor who studies cells and body tissues. If cancer cells are found in the removed tissue you may be offered further treatment after your operation. This may be chemotherapy. Or if you had chemoradiation before surgery, you may be offered immunotherapy treatment.

Treating oesophageal cancer that has spread

Advanced stage oesophageal cancer is when the cancer has spread beyond the oesophagus. This may be to lymph nodes or other parts of the body, such as the liver, lungs or stomach.

If you have advanced squamous cell oesophageal cancer, you may have chemotherapy or immunotherapy. These may be given on their own, or together.

If you have advanced adenocarcinoma of the oesophagus, you may have chemotherapy or immunotherapy. Or you may have a combination of both.

Targeted therapy drugs are sometimes used to treated advanced oesophageal cancer. Your cancer doctor can talk to you more about this.

You might be offered treatment as part of a research trial (clinical trial). Your cancer doctor can tell you if there are any suitable trials for you to take part in.

Difficulty swallowing

If you have difficulty swallowing, you may have 1 of the following treatments:

  • Your cancer doctor may suggest putting a wire mesh tube, called a stent, into the oesophagus. This can help keep it open, so food can pass through more easily.
  • External radiotherapy or internal radiotherapy (brachytherapy) can be used to help with swallowing difficulties.
  • Laser therapy may be used to help with swallowing difficulties.
  • You might have a treatment to help stretch the oesophagus.
  • Your cancer doctor may recommend you have a feeding tube to make sure you are getting enough food. We have more information on feeding tubes and nutritional support.

About our information

This information has been written, revised and edited by Macmillan Cancer Support’s Cancer Information Development team. It has been reviewed by expert medical and health professionals and people living with cancer.

Dr Chris Jones

Reviewer

Speciality Registrar in Clinical Oncologist and Clinical Lecturer in Clinical Oncology

Date reviewed

Reviewed: 01 November 2024
|
Next review: 01 November 2027
Trusted Information Creator - Patient Information Forum
Trusted Information Creator - Patient Information Forum

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