Anal fissure after pelvic radiotherapy

An anal fissure is a split in the skin of the anus. This can be a side effect of pelvic radiotherapy.

What is an anal fissure?

After pelvic radiotherapy, the skin of the anus may become narrower and less stretchy. Sometimes a split develops in the skin of the anus. This is called an anal fissure. It can cause a sharp, intense pain when you pass a stools (poo).

Anal fissure treatment

Your doctor can usually prescribe creams you apply to the area that help it heal. It is important to avoid getting constipated, because this can make a fissure worse. Your doctor may prescribe a laxative to make it easier for you to go to the toilet.

If the fissure does not get better

Your doctor may advise injections of botulinum toxin A (Botox®). These are given into the tissue that lines the anus. Botox® causes the muscle to relax. This reduces the pain and increases the blood flow, which helps the fissure to heal.

Some people may need a minor operation to make a small cut in the muscle around the anus. This releases the tension in the muscle and allows the fissure to heal. You usually have this operation under a general anaesthetic, as a day patient.

About our information

This information has been written, revised and edited by Macmillan Cancer Support’s Cancer Information Development team. It has been reviewed by expert medical and health professionals and people living with cancer.

Date reviewed

Reviewed: 01 July 2024
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Next review: 01 July 2027
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