Prostate cancer treatment

Your doctor will explain the different treatment options for early or locally advanced prostate cancer. Together you can decide on the best treatment for you. Treatments may cure the cancer or keep it under control for many years.

Treatment options for prostate cancer

Your treatment for prostate cancer will depend on:

  • your general health
  • your age
  • the risk group if you have early prostate cancer
  • the Gleason score and cancer grade
  • the stage of the cancer
  • your preferences.

We have more information about staging, grading and risk groups.

Your preferences and how you feel about treatments is a personal choice. What is important to one person might not be to someone else.

Multidisciplinary team (MDT) for prostate cancer

After your test results, you and your doctor start to talk about your treatment. Your doctor usually meets with other specialists to get their opinions too.

A team of specialists meets to talk about the best treatment for you. This is called a multidisciplinary team (MDT).

The MDT looks at national treatment guidelines or the latest evidence for the type of cancer. If you have any treatment preferences, your doctor will tell them about this.

The MDT meeting will usually include the following professionals:

  • Urologist or urological surgeon is a doctor who treats problems with and does surgery on the prostate, kidneys, bladder and male reproductive system.
  • Clinical oncologist is a doctor who uses radiotherapy, chemotherapy and other anti-cancer drugs to treat people with cancer.
  • Medical oncologist is a doctor who uses chemotherapy and other anti-cancer drugs to treat people with cancer.
  • Clinical nurse specialist is a nurse who gives information about cancer, and support during treatment.
  • Radiologist is a doctor who looks at scans and x-rays to diagnose problems.
  • Pathologist is a doctor who looks at cells or body tissue under a microscope to diagnose cancer.

The MDT may also include:

  • Pathway co-ordinator, who can provide information and guidance for other needs, such as financial support.
  • Advanced nurse practitioners, who are specialist nurses for types of cancer and treatments –for example, surgical advanced nurse practitioners.
  • Advanced clinical practitioner, who is an expert healthcare professional, such as a nurse, who works with doctors to help assess people with cancer and manage their treatment and care.
  • Other healthcare professionals – for example, physiotherapists, occupational therapists or pharmacists, who are specialists in cancer and treatments.

Other people will be involved in your care. This includes medical and nursing staff on the wards or in different departments. If you have radiotherapy, you will meet a therapeutic radiographer. They are an expert in radiotherapy and are specially trained to give you treatment. They can also give you support, advice and information.

Treatments for prostate cancer

The main types of treatment for early stage prostate cancer or locally advanced prostate cancer include:

  • Surgery to remove the prostate

    This is called radical prostatectomy. It is usually done with keyhole surgery (laparoscopic surgery) or robot-assisted surgery, which means you usually recover quickly. Surgery to remove the prostate is not commonly done to treat locally advanced prostate cancer.

  • External beam radiotherapy

    External beam radiotherapy uses high-energy x-rays to destroy the cancer cells. You usually have this over a few weeks as an outpatient.

  • Internal radiotherapy (brachytherapy)

    Brachytherapy gives high doses of radiation directly to the prostate. It is often given as a boost with external radiotherapy. Brachytherapy may be given on its own for some early prostate cancers.

  • Active surveillance

    Active surveillance is used to monitor the cancer, which can help to avoid unnecessary treatment. Active surveillance involves having a PSA test every few months, and a multiparametric MRI scan (mpMRI scan) every 1 or 2 years.

  • Hormonal therapy

    Hormonal therapy helps reduce the amount of testosterone in the body. It is often given before and after radiotherapy. Hormonal therapy is sometimes given on its own to control the cancer if you do not want other treatments.

  • Watchful waiting

    Watchful waiting is a type of monitoring that does not involve scans or biopsies. The aim of watchful waiting is to control the symptoms of prostate cancer rather than cure it. If there are signs the cancer is growing or causing symptoms, your doctor will talk to you about starting hormonal therapy.

  • High-intensity focused ultrasound (HIFC) or cryotherapy

    High-intensity focused ultrasound (HIFC) or cryotherapy are treatments that use heat or cold to destroy prostate cancer cells. These treatments are not routinely available in all NHS hospitals. Doctors still do not know enough about how effective cryotherapy and HIFU are when compared to existing treatments for early prostate cancer.

Prostate cancer risk groups and treatment

In prostate cancer, doctors offer treatments based on the risk group of the cancer using the Cambridge Prognostic Group system (CPG). Your doctor may still describe your risk as low, moderate or high.

  • Low risk prostate cancer (CPG1 or 2)

    Prostate cancer in CPG risk group 1 or 2 grows very slowly. It is not likely to cause problems for a long time. Sometimes the cancer will never cause problems.

  • Intermediate risk prostate cancer (CPG3)

    If the cancer is CPG risk group 3, and you are otherwise fit and well, you usually have treatment with either radiotherapy or surgery. If you have radiotherapy, you may also have brachytherapy. This is sometimes called a boost. You will also usually have hormonal therapy for 6 months before, during and after radiotherapy.

    You may decide to have active surveillance if you do not want treatment with surgery or radiotherapy straight away. If you do not want surgery or radiotherapy at all, you may choose watchful waiting.

  • High risk prostate cancer (CPG4 or 5)

    For cancer in CPG risk groups 4 or 5, you usually need more treatment to try and cure the cancer as there is a higher risk of it spreading. You can have treatment with either a radical prostatectomy or radiotherapy. You may also have brachytherapy and hormonal therapy. Hormonal therapy may continue for up to 3 years. Some people may also be given another hormonal therapy called abiraterone for 2 years. Your cancer doctor can talk to you about whether this is an option for you. 

Making treatment decisions

You and your doctor can decide together on the best treatment plan for you. Your doctor is an expert in the best treatments. But you know your preferences and what is important to you. You can decide how involved you want to be in your treatment plan.

You can use the online decision aid called Predict. You can also read more and compare treatments on the infopool.

Sometimes doctors need to review a treatment plan. This may be when more information about the cancer becomes available – for example, when the doctor knows the results of surgery to remove the cancer. It may mean making more decisions with your doctor.

When you make treatment decisions, there are different things you may want to think about:

  • How you feel about different treatments.
  • How you might cope with treatments if you have other health conditions. For example, you may prefer not to have surgery if you have heart problems. Or you may want to avoid radiotherapy if you have a bowel condition – some bowel problems mean that radiotherapy is not suitable.
  • How much side effects are likely to bother you – for example, erection difficulties. If active surveillance is suitable, you may be able to avoid erectile dysfunction (ED) caused by surgery or radiotherapy. After surgery, you are more likely to get ED straight away.
  • Whether the cancer is very unlikely to cause you problems over your lifetime. If it is unlikely, monitoring the cancer with active surveillance or watchful waiting may be more suitable for you.
  • What your treatment options would be if the cancer came back. You may be able to have radiotherapy after surgery. But it may not be possible to have surgery if you have already had radiotherapy.

Treatment effects on your sex life

The effects of treatment on your sex life and relationships may be a big concern for you. Your doctor and nurse will explain the likely effects of treatments on your sex life. You may worry about talking about your sex life with your healthcare team. But it is important to ask questions. There are different treatments and support available to improve sexual difficulties.

We have more information about prostate cancer and sex.

Fertility

Most treatments for prostate cancer are likely to cause infertility. This means you will no longer be able to make someone pregnant. If fertility is a concern for you, contact your healthcare team before treatment. We have more information about fertility.

Getting support

Macmillan is here to support you. If you would like to talk, you can do the following:

About our information

This information has been written, revised and edited by Macmillan Cancer Support’s Cancer Information Development team. It has been reviewed by expert medical and health professionals and people living with cancer.

  • References

    Below is a sample of the sources used in our prostate cancer information. If you would like more information about the sources we use, please contact us at informationproductionteam@macmillan.org.uk

     

    National Institute for Health and Care Excellence (NICE). Prostate cancer: diagnosis and management. NICE Guideline [NG131]. Published: 09 May 2019. Last updated: 15 December 2021. Available from: www.nice.org.uk/guidance/ng131 [accessed March 2024].

     

    Castro E, Fizazi K, Heidenreich A, Ost P, Parker C, Procopio G, et al. Prostate cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Annals of Oncology. 2020; 31(9): 1119–1134. Available from: www.annalsofoncology.org/article/S0923-7534(20)39898-7/fulltext [accessed March 2024].

Dr Ursula McGovern

Reviewer

Consultant Medical Oncologist & Honorary Associate Professor

University College Hospitals, London

Date reviewed

Reviewed: 01 October 2025
|
Next review: 01 October 2028
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Trusted Information Creator - Patient Information Forum

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