Causes and risk factors of lung cancer
There are certain things that can increase the risk of developing lung cancer. These are called risk factors. Having a risk factor does not mean you will get cancer. And not having a risk factor does not mean that you will not get it.
If you are worried about lung cancer and would like to talk to someone, we're here. You can:
Smoking tobacco is the cause of most lung cancers and the biggest risk factor. This includes smoking cigarettes, cigars and pipes. The more you smoke, the bigger your risk.
Around 9 out of 10 people who get lung cancer (90%) are smokers or ex-smokers. Starting smoking at a younger age increases the risk. In the UK, 72% of lung cancer cases are caused by smoking.
When people stop smoking, their risk of lung cancer gets lower over time. After 12 years of not smoking, the risk of getting lung cancer is about 70% lower than it is for people who still smoke. After about 15 years, it is almost the same as a non-smoker.
People who do not smoke can also get lung cancer, but their risk is much lower. About 1 in 10 people who get lung cancer (10%) have never smoked.
We have more information about giving up smoking.
Breathing in other people’s cigarette smoke is called passive or second-hand smoking. It can slightly increase the risk of lung cancer. The risk is much lower than if you smoke yourself. In the UK, smoking is now banned in enclosed public places and workplaces.
Asbestos is a material that was previously used in the building industry. People who have been in prolonged or close contact with asbestos have a higher risk of getting lung cancer. The risk is greater if they smoke.
Exposure to asbestos also increases the risk of cancer of the pleura. This is called mesothelioma. The pleura are the membranes that cover the lungs.
If you worked with asbestos and have lung cancer or mesothelioma, you may be able to claim compensation. Your lung cancer specialist nurse can give you advice on this.
In certain parts of the UK, a natural gas called radon can pass from the soil into the foundations of buildings. Exposure to high levels of radon is not common. But it can increase the risk of developing lung cancer, particularly in people who also smoke.
Recent research has shown that air pollution can increase the risk of lung cancer. The risk is linked to air quality and how much pollution a person is exposed to. For most people, the risk is very small. Smoking is the major risk factor for lung cancer.
Rarely, contact with certain chemicals and substances can increase the risk of lung cancer. Contact with these substances is usually through work. For example, you have an increased risk if you work with:
Being exposed to diesel fumes through work can also increase lung cancer risk. For most people, the risk is very small.
People have a slightly increased risk of lung cancer if they have previously had radiotherapy to the chest to treat:
The risk is higher if they smoke. The benefits of this treatment far outweigh the risk of developing lung cancer, especially as these cancers can be cured.
Having lowered immunity because of illness or treatment can increase the risk of lung cancer. People have a lowered immune system if they:
- have HIV or Aids
- take immunosuppressant drugs after an organ transplant.
People with a parent who had lung cancer have an increased risk of developing it. People who have a brother or sister with lung cancer have a higher risk, especially if they were diagnosed at a younger age.
Doctors do not know why this is. It could be caused by a lung cancer gene that runs in the family (inherited). Or it could be caused by shared risk factors such as smoking.
If you are worried about lung cancer in your family, you may find it helpful to talk to your GP.
Below is a sample of the sources used in our lung cancer information. If you would like more information about the sources we use, please contact us at email@example.com
National Institute for Health and Care Excellence (NICE). Lung cancer – Diagnosis and management. Clinical guideline 2019.
Metastatic non-small cell lung cancer: ESMO clinical practice guidelines for diagnosis, treatment and follow-up. 2018.
European Society for Medical Oncology (ESMO). Early and locally advanced non-small-cell lung cancer (NSCLC): ESMO clinical practice guidelines for diagnosis, treatment and follow-up. 2017.
This information has been written, revised and edited by Macmillan Cancer Support’s Cancer Information Development team. It has been reviewed by expert medical and health professionals and people living with cancer. It has been approved by Senior Medical Editor, Dr David Gilligan, Consultant Clinical Oncologist.
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