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Histology independent therapies (HITs)

Booklet
Published: 01 Jan 2025
Next review: 01 Jan 2027
Edition: 2
MAC19456_E02_HITs_thumbnail

This leaflet is about histology independent therapies (HITs). HITs are a type of cancer treatment used to treat cancers that have a certain gene change.

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You can also download a copy of this booklet on Macmillan Orders with ID: MAC19456
Published: 01 Jan 2025
Next review: 01 Jan 2027
Edition: 2

This leaflet is about histology independent therapies (HITs). HITs are a type of cancer treatment used to treat cancers that have a certain gene change.

About this leaflet

There are 2 HIT drugs currently available. These drugs are larotrectinib (Vitrakvi®) and entrectinib (Rozlytrek®). They can be used to treat people with a cancer that has a gene change called NTRK gene fusion.

 

This leaflet has been developed in partnership with NHS England, the charities Cancer Research UK, Sarcoma UK and Teenage Cancer Trust, and a working group of people affected by cancer. It is supported by the Accelerated Access Collaborative at NHS England.

 

Visit our online information about histology independent therapies (HITs).

 

We want everyone affected by cancer to feel our information is written for them. To do this we use plain English and we try to make it accessible and relevant to the widest range of people. Read more about how we produce our information.