Personalised cancer vaccines

Blog
Published: 31 May 2024
You may have recently seen a news story about cancer patients trialling a new type of treatment that uses personalised vaccines. If you now have questions about cancer vaccines and clinical trials, we have answers to some of the most common questions in this blog.

Maria Lavery Senior Cancer Information Development Nurse at Macmillan Cancer Support

Personalised cancer vaccines 

In May 2024, NHS England used a personalised vaccine to treat a patient with bowel cancer for the first time. The treatment has been given as part of a clinical trial through the NHS England Cancer Vaccine Launch Pad scheme

What are cancer vaccines? 

Cancer vaccines are a type of immunotherapy. This means they use the body’s own immune system to treat cancer. They are given to help train the immune system to find and kill cancer cells and prevent them from coming back. 


We often think about vaccines as something that prevents an illness or infection. This cancer vaccine doesn’t work like that. It isn’t given to prevent cancer. But it can be used to treat cancer after other treatments, such as surgery. It may help reduce the risk of cancer recurrence. 

 

How is the cancer vaccine made? 

Each cancer vaccine is made individually for each person. A sample from the cancer is carefully analysed. Information about the genetics of the sample is used to create a personalised cancer vaccine. 
The process usually takes a few weeks, but it produces a treatment that is tailored to that person. 

We have more information about how the genes in cancer cells can be used to develop or plan cancer treatment. Find out more about:

Who can join the cancer vaccine trials? 

The trials are currently only available in England. An NHS scheme called the Cancer Vaccine Launch Pad is recruiting people with cancer and matching them into certain clinical trials. Your cancer team or GP can explain more about trials that may be suitable for you. 

 

The first trials are expected to study colorectal, skin, lung, bladder, pancreatic and kidney cancer. Other cancers may be included in the future. You need to meet certain criteria to take part in the cancer vaccine trial.

 

We have more information if you are thinking about taking part in a clinical trial

 

Do cancer vaccines work?

Research into cancer vaccines is still at an early stage and this is not yet an approved standard treatment. But trials already show that cancer vaccines can be used to kill off any remaining tumour cells after surgery and help to cut the risk of cancer returning.
  • A father and his daughter sitting outside
    Blogs 06 Nov 2023
    You might not describe yourself as a carer. But looking after someone with cancer can have an impact on your life. There is support and information available that can help.
  • A woman sleeping on the sofa
    Blogs 28 Feb 2023
    Sleep disturbance or difficulty sleeping is a common problem for people living with cancer. If you are struggling to get enough sleep, you may be feeling stressed and anxious. You may worry about how...
  • Vivek, an Asian man Ia working on a computer.
    Blogs 07 Feb 2024
    Get expert information and advice from Macmillan about work rights, financial support options, sick pay and self-employment for people with cancer.