Common questions about painkillers

Some people have concerns about pain medicines, especially strong painkillers like morphine. It can help to read answers to common questions about painkillers before you start taking them.

Questions you may have about painkillers

If you are worried about the pain medicines you have been prescribed, you may be less likely to take them. This can make it harder to control the pain.

Talk to your doctor or nurse about any concerns or questions you have. Your healthcare team is used to talking about these things. There is no silly question. Being able to talk through your concerns will usually help you feel more comfortable about taking the drugs.

We have some questions and answers below that may help.

  • When should I start taking painkillers?

    Start taking your painkillers as prescribed by your doctor, when you have pain. Sometimes people think they should delay using painkillers for as long as possible. But there is no need to delay taking them. If you wait until the pain gets really bad, it will be harder to get the pain under control. It also means you may be in pain when you do not need to be.

  • Does taking a strong painkiller mean the cancer is advanced?

    Having morphine does not mean the cancer is more serious. Doctors use strong painkillers (such as morphine) to treat severe pain from other causes as well as cancer. It is important that you have the right painkiller at the right dose to treat your pain. If your pain improves, your doctor or specialist palliative care nurse may reduce the dose of painkiller or change you to a milder painkiller. 

  • Is there a maximum dose for strong painkillers?

    There is no maximum dose for strong painkillers. The right dose is the one that works for you. If you take your painkillers as prescribed, you will not overdose.

    If you have pain, do not increase the dose without talking to your doctor or specialist palliative care nurse first. It can be dangerous to change your dose without guidance from your doctor or nurse.

  • Will I become addicted to painkillers? 

    Addiction is rare when a strong painkiller is used correctly to relieve cancer pain as prescribed by your doctor. If the painkiller is helping to relieve your pain, you are unlikely to become addicted to it.

    If you are worried about becoming addicted, talk to your doctor or nurse. If your family and friends are also concerned, you could ask them to come to an appointment with you.

  • When can I stop taking a strong painkiller?

    If your pain improves, you may be able to reduce and then stop taking a strong painkiller. But it is important that you do not suddenly stop taking it. Talk to your specialist palliative care nurse first. They will explain if it is a good idea to reduce your dose. They will also tell you how to do this gradually to avoid pain and withdrawal problems. Withdrawal is when your body finds it difficult to cope with suddenly stopping or reducing a drug that you have been taking.

    Signs of withdrawal include:

    • diarrhoea
    • cramping pains in the stomach and bowel
    • sickness
    • sweating
    • feeling restless or agitated.

    Contact your doctor straight away if you have these symptoms.

  • Can I drink alcohol if I am taking painkillers?

    Drinking alcohol with milder, non-opioid painkillers is not usually a problem. If you are taking strong painkillers, you can usually drink small amounts of alcohol. This is around 1 or 2 units (a small glass of wine) per day. But you may find it makes you sleepier. Some people find it has a stronger effect on them and makes them feel unwell. It may be best to not drink alcohol if you can.

    Your painkillers will have a patient information leaflet. This will have information about alcohol. You can also ask your doctor, nurse or pharmacist for more information about the painkillers you are taking.

  • Can I drive if I am taking strong painkillers?

    When you first start taking strong painkillers, they may make you feel tired and drowsy. You may not be able to concentrate, and your reactions may be slow. You may also be taking other drugs for pain which can make you drowsy and affect driving.

    You should not drive or operate machinery for a few days:

    • when you start taking strong painkillers
    • if your dose of painkiller has been changed.

    If you are not drowsy and you feel able to drive safely after this time has passed, you should usually be okay to drive. Do not drive immediately after taking an extra (breakthrough) dose of a strong painkiller.

    Painkillers can affect people differently. It is your responsibility to judge if you feel safe and fit to drive. Avoid driving if you:

    • feel sleepy or drowsy
    • are struggling with co-ordination
    • feel dizzy
    • are having problems with your eyesight
    • find it hard to concentrate due to the pain or as a side effect of the painkillers
    • think you may be unable to do an emergency stop.

    If you are not sure, speak to your cancer doctor, nurse, palliative care team or GP.

    Keep your first drive short and easy. Take another driver with you in case you feel drowsy while you are out. If you are worried that you may not be safe to drive, ask your doctor for advice.

    You do not have to tell the DVLA or the DVA in Northern Ireland if you are taking strong painkillers. But they may need to know about your cancer. Your doctor or specialist nurse can give you more information.

    It is a good idea to tell your insurance company if your ability to drive may be affected. Each company is different, but your insurance may not be valid if you do not tell them. Make sure you know what your doctor’s advice is before you contact your insurance company.

  • Will I be breaking the law if I drive while I am taking strong painkillers?

    It is an offence to drive with certain drugs above certain limits in your body. This includes some prescription medicines.

    You may be prosecuted if you have drugs in your body that affect your driving, even if you have been prescribed the drugs.

    You will not be breaking the law if the painkillers are not affecting your ability to drive safely, and you are:

    • taking them exactly as your doctor prescribed them
    • following the information that came with the painkillers.

    The police can stop people who are driving and do tests to check whether they have taken any drugs. It is a good idea to keep a copy of your prescription with you, as well as the painkiller packaging.

    If you are not sure whether you are able to drive, you should not drive. Your doctor, specialist nurse or pharmacist can tell you more about this.

  • Can I travel with my painkillers?

    Some countries limit the amount of particular drugs that can be taken into the country. There are restrictions about taking drugs like morphine into some countries.

    We have more information about taking medicines abroad

  • How should I store my painkillers?

    Organising your medicines helps to make sure you store them all safely. It may also help you remember to take them exactly as your doctor prescribed.

    Here are some tips for storing your medicines:

    • Check the expiry date.
    • Keep them in their original bottle or packet where you can clearly read the label.
    • Keep them in a cool, dry place. Store them as directed by the leaflet inside.
    • Keep them where children cannot see or reach them. You might want to lock away strong painkillers.
    • Return any unused medicines to a pharmacy (chemist) so they can dispose of them properly. Do not put them in the bin or down the toilet.
  • How can I remember when to take my painkillers?

    It can be hard to remember to take your painkillers, especially if you have a lot of medicines to take. You may be taking more than 1 painkiller, as well as other medicines.

    Here are some tips to help you remember when to take them:

    • make taking your medicines part of your daily routine – for example, taking them after meals, depending on the instructions
    • set an alarm on your mobile phone or computer to remind you
    • write yourself a reminder
    • ask your partner, relative or friend to remind you to take them
    • use the pain diary to help you keep track of when to take your drugs.
    • If you are taking several different drugs, you may find it helpful to write down:

    • the drugs you are taking
    • what they are for
    • their doses
    • when you need to take them.
    • You may find it easier to arrange your drugs in a blister pack or dosette box. These have separate compartments which clearly show the day and time when you should take your medicines. These are made up by your pharmacist. Your GP may be able to organise this with your pharmacist. You can also ask your pharmacist for more information if you think this could help you.

      If you have a smartphone there are free apps you can download to help you remember to take your medicines.

About our information

This information has been written, revised and edited by Macmillan Cancer Support’s Cancer Information Development team. It has been reviewed by expert medical and health professionals and people living with cancer.

  • References
    Below is a sample of the sources used in our cancer pain information. If you would like more information about the sources we use, please contact us at informationproductionteam@macmillan.org.uk

    ESMO Management of Cancer Pain in Adult Patients. ESMO Clinical Practice Guidelines. 2018. Available from: www.esmo.org/guidelines/esmo-clinical-practice-guideline-cancer-pain [accessed 24/03/2025].

    NICE Palliative cancer care: Pain. 2025. Available from: cks.nice.org.uk/topics/palliative-cancer-care-pain/management/managing-pain-non-emergency/#management-of-breakthrough-pain [accessed 17/02/2025].

    Scottish Palliative Care Guidelines. Available from: https://rightdecisions.scot.nhs.uk/scottish-palliative-care-guidelines/ [accessed 17/02/2025].
Dr Ollie Minton, Macmillan National Clinical Adviser and Consultant in Palliative Medicine.

Professor Ollie Minton

Reviewer

Consultant in Palliative Medicine

University Hospitals Sussex

Date reviewed

Reviewed: 01 August 2025
|
Next review: 01 August 2028
Trusted Information Creator - Patient Information Forum
Trusted Information Creator - Patient Information Forum

Our cancer information meets the PIF TICK quality mark.

This means it is easy to use, up-to-date and based on the latest evidence. Learn more about how we produce our information.

The language we use


We want everyone affected by cancer to feel our information is written for them.


We want our information to be as clear as possible. To do this, we try to:

  • use plain English
  • explain medical words
  • use short sentences
  • use illustrations to explain text
  • structure the information clearly
  • make sure important points are clear.

We use gender-inclusive language and talk to our readers as ‘you’ so that everyone feels included. Where clinically necessary we use the terms ‘men’ and ‘women’ or ‘male’ and ‘female’. For example, we do so when talking about parts of the body or mentioning statistics or research about who is affected.


You can read more about how we produce our information here.