A doctor or specially trained nurse will do the lumbar puncture. Your doctor or nurse will usually give you a local anaesthetic first. Then they will insert a hollow needle between 2 of the spinal bones in the lower back. This can be used to take a sample of cerebrospinal fluid (CSF) for testing.
A lumbar puncture can be done in an outpatients department or on a ward at the hospital.
Intrathecal chemotherapy is when chemotherapy is given into the fluid around the spinal cord during a lumbar puncture.