Photodynamic therapy (PTD) for skin cancer

Photodynamic therapy (PDT) uses light sources combined with a light-sensitive drug to destroy cancer cells. PDT is particularly useful in areas where the skin cancer develops directly over bone, such as on the shins and hands. It is also useful for superficial BCCs.

Before treatment, the doctor or nurse may remove any scabs from the area. Then they will put a cream containing the light-sensitive drug onto the area. They will usually cover this with a dressing. You then wait for around three hours before having the light treatment. This allows the cream to soak into the layers of the skin.

Next, the doctor or nurse will clean the area. Then they will shine a special light directly onto your skin. The light treatment usually lasts between 8 and 45 minutes, depending on the light source they use. Some people may find they get a stinging or burning feeling in the treatment area. Tell your doctor or nurse if you are uncomfortable. They can give you something to help.

After this, they will put a dressing over the area to cover it and protect it from light. Keep the dressing on for up to 36 hours after your treatment. Your doctor or nurse will give you instructions about this before you leave hospital.

After having PDT, a crust usually forms over the treated area. This crust will fall off naturally after a few weeks, leaving the healed, new skin underneath.

Usually, only one treatment of PDT is needed. But occasionally you may need two or three if the skin cancer is thick. Your doctor or nurse will explain how you will have the treatment and how many you may need.

We have more information about photodynamic therapy (PDT).

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Immunotherapy for skin cancer

Immunotherapy uses the body’s immune system to attack cancer cells. Immunotherapy cream can be used to treat some small skin cancers.