Lymphoma symptoms

The most common symptom of lymphoma is a painless swelling or lump in the lymph nodes in the neck, armpit or groin.

Common symptoms of lymphoma

The most common symptom of lymphoma is a painless swelling or lump in the neck, armpit or groin. This is caused by lymphoma cells building up in the lymph nodes, which makes them bigger.

In this video, Jill, a Cancer Information Nurse, lists symptoms of lymphoma. Understanding these lymphoma symptoms can help with earlier recognition and treatment.

 

There are different causes of swollen lymph nodes. But if you notice a painless, swollen lymph node, it is important to get it checked by your GP.

Lymph nodes are part of the lymphatic system, which helps protect your body from infection and disease. When the lymph nodes are fighting infection, they often swell and become sore to touch.

If there is cancer in the lymph nodes, they may swell, but are usually painless.

Other symptoms of lymphoma

Some people have other symptoms, depending on where the lymphoma is in their body.

Signs and symptoms of lymphoma

The body is shown. Painless swollen lymph nodes are highlighted in red next to the neck, armpit and groin area.
Image: The diagram shows the outline of a front facing body. There are red marks on 1 side of the neck, an armpit, and 1 side of the groin. The red marks show where there is a swollen lymph node.

If the lymphoma is in the chest area, symptoms may include:

  • a cough
  • difficulty swallowing
  • shortness of breath.

If the lymphoma is in the stomach or bowel, symptoms may include:

  • indigestion
  • tummy pain
  • weight loss.

Indigestion is also called heartburn or acid reflux. Symptoms include:

  • a burning feeling in the chest
  • burping
  • feeling full and bloated.

Sometimes pressure from swollen lymph nodes may cause pain. For example, it can cause pain in an area such as the tummy (abdomen). This is not common.

A symptom of Hodgkin lymphoma, is aching or painful swollen lymph nodes soon after drinking alcohol. But this is rare.

Lymphoma can also cause symptoms that affect the whole body, including:

  • repeat infections
  • heavy, drenching sweats, especially at night
  • high temperatures or fevers over 38˚C (100.4˚F) that come and go without any obvious cause
  • unexplained weight loss
  • tiredness
  • itching all over the body that does not go away.

The following types of lymphoma may cause other symptoms:

B symptoms

Lymphoma B symptoms include:

  • heavy, drenching night sweats
  • unexplained high temperatures
  • unexplained weight loss.

Doctors use information about B symptoms to help stage lymphoma and plan treatment.

If lymphoma is in the bone marrow

If the lymphoma is in the bone marrow it can reduce the number of blood cells in your body. Bone marrow is material in the middle of bones where blood cells are made.

Lymphoma in the bone marrow can cause:

  • tiredness, if you do not have enough red blood cells (anaemia)
  • difficulty fighting infections, if you do not have enough white blood cells
  • bruising or bleeding, if you do not have enough blood-clotting cells (platelets).

Lymphoma in children and younger adults

Lymphoma is more common in people who are over 50. But it can happen at any age. We can help teenagers and young adults find more information and support. Lymphoma Action provides information about lymphoma in children.

About our information

This information has been written, revised and edited by Macmillan Cancer Support’s Cancer Information Development team. It has been reviewed by expert medical and health professionals and people living with cancer.

  • References

    Below is a sample of the sources used in our lymphoma information. If you would like more information about the sources we use, please contact us at informationproductionteam@macmillan.org.uk

     

    Follows GA, Barrington SF, et al. Guideline for the first-line management of Classical Hodgkin Lymphoma — A British Society for Haematology guideline. Br J Haematol, 2022; 197, 558– 572. [accessed April 2024].

     

    Fox CP, Chaganti S, McIlroy G, et al. The management of newly diagnosed large B-cell lymphoma: A British Society for Haematology Guideline. Br J Haematol. 2024; 204(4):1178–92. [accessed April 2024].

     

    McKay P, Fielding P, et al. Guidelines for the investigation and management of nodular lymphocyte predominant Hodgkin lymphoma. Br J Haematol, 2015; 172, 32-43. [accessed April 2024].

     

    McNamara C, Montoto S, et al. The investigation and management of follicular lymphoma. Br J Haematol, 2020; 191, 363-381. [accessed April 2024].

     

    National Institute for Health and Care Excellence. Non-Hodgkin’s lymphoma: diagnosis and management. NICE guideline [NG52]. Published: 20 July 2016. Last update Oct 2021. [accessed April 2024].

Date reviewed

Reviewed: 01 August 2025
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Next review: 01 August 2028
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