The stage of a lymphoma is usually described using numbers from 1 to 4.
There is one area of lymphoma only. This may be one group of lymph nodes or another part of the lymphatic system.
There are two or more areas of lymphoma on the same side of the diaphragm (the sheet of muscle underneath the lungs).
There are areas of lymphoma above and below the diaphragm.
There are areas of lymphoma outside and separate from the lymphatic system. For example, this could be in organs such as the bone marrow, liver or lungs.
Stages 1 and 2 are also called early-stage, limited lymphoma.
If stage 1 or 2 lymphoma has grown into nearby areas of tissue, this is called extra-nodal disease. The letter E may be added after the stage number to show it is extra-nodal disease, for example stage 1E.
Stages 3 and 4 are also called advanced lymphoma.
If you have any B symptoms, the letter B is added after the stage number, for example stage 1B. B symptoms are:
- heavy, drenching night sweats
- unexplained high temperatures
- unexplained weight loss.
If you do not have any of these symptoms, the letter A is used instead, for example stage 1A.
Below is a sample of the sources used in our Hodgkin lymphoma (HL) information. If you would like more information about the sources we use, please contact us at firstname.lastname@example.org
Collins G, et al. Guideline on the management of primary resistant and relapsed classical Hodgkin lymphoma. British Journal of Haematology. 2014. 164: 39–52. Available from: http://onlinelibrary.wiley.com/doi/10.1111/bjh.12582/pdf
Follows G, et al. Guidelines for the first line management of classical Hodgkin lymphoma. British Journal of Haematology. 2014. 166: 34–49. Available from: http://onlinelibrary.wiley.com/doi/10.1111/bjh.12878/pdf
McKay P, et al. Guidelines for the investigation and management of nodular lymphocyte predominant Hodgkin lymphoma. British Journal of Haematology. 2016. 172: 32–43. Available from: http://onlinelibrary.wiley.com/doi/10.1111/bjh.13842/epdf
Treleaven J, et al. Guidelines on the use of irradiated blood components prepared by the British Committee for Standards in Haematology blood transfusion task force. British Journal of Haematology. 2011. 152: 35–51. Available from: http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2141.2010.08444.x/full.
This information has been written, revised and edited by Macmillan Cancer Support’s Cancer Information Development team. It has been reviewed by expert medical and health professionals and people living with cancer. It has been approved by Senior Medical Editors, Dr Anne Parker, Consultant Haematologist; and Professor Rajnish Gupta, Macmillan Consultant Medical Oncologist.
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