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Macmillan and Cancerbackup merged in 2008. Together we provide free, high quality information for people affected by cancer through our publications, website and phone service. Find out more| .
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If the result of your cervical screening test shows that there are changes in the cells of the cervix, you should have the chance to discuss this with your GP or practice nurse. You can also discuss it with one of our cancer support specialists|.
Most abnormal results from screening tests show only very minor changes. These are called borderline or mild changes or mild dyskaryosis. Many of these will go back to normal on their own, so your GP may simply arrange for you to have further screening tests 6, 12 and 24 months later. If you smoke, it may help if you try to give up as this will make it more likely that your cervical cells go back to normal.
If your second screening test still shows abnormal cells, your GP or practice nurse may then arrange for you to have some further tests.
On the other hand, some doctors will refer you for further investigation after just one abnormal test result, however minor.
A smaller number of women will have moderate or severe changes (CIN 2 or CIN 3). These are known as moderate or severe dyskaryosis. If this is the case, your GP or practice nurse will suggest that you have a further test, known as colposcopy, within a few weeks.
If you need to have colposcopy you will be referred to your local colposcopy unit, which is usually at a hospital outpatients clinic. You do not normally have to stay overnight. Almost all hospitals with gynaecological units have the facilities to do colposcopy.
Colposcopy shows the cervix in detail using a colposcope. A colposcope is a specially adapted type of microscope. It acts like a magnifying glass so that the colposcopist can see the whole cervix in more detail.
Colposcopy can be carried out by a specialist doctor or a nurse colposcopist. Doctors and colposcopy nurses follow national guidelines when deciding whether you need further tests or treatment. Before your test you will have a chance to discuss your screening test results, and any worries that you may have, with the doctors or nurses at the clinic.
You will be helped to position yourself on a specially-designed chair or examination table. When you are lying comfortably, the colposcopist will use a speculum – in the same way as in the screening test – to hold your vagina open. The cervix is then painted with a liquid to make the abnormal areas show up more clearly. A light is shone onto the cervix and the doctor will look through the colposcope (which stays outside your body) to examine the surface of the cervix. A small sample (approximately the size of a grain of rice) of cells from the cervix (a biopsy) may be taken to be looked at under a microscope.
Colposcopy takes a bit longer than the screening test, about 15–20 minutes. It is not usually painful, but you may feel some pain if a biopsy is taken. You may also have some slight bleeding for a couple of days afterwards.
If the abnormal area still cannot be seen clearly with a colposcope, the colposcopist may arrange for you to have a cone biopsy or LLETZ (large loop excision of the transformation zone).
The doctor takes a small cone-shaped section of the abnormal tissue from the cervix for examination under a microscope. This is normally done under local anaesthetic, although sometimes a general anaesthetic may be used. Looking at the tissue that has been removed can show whether the abnormal cells are CIN 1, 2 or 3 or whether deeper levels of the cervix are affected.
The dashed lines show the area of the cervix that is removed in a cone biopsy
Afterwards, a small pack of gauze (like a tampon) may be put into the vagina to prevent bleeding. This is usually removed within 24 hours.
It is normal to have some light bleeding and discharge for a few days after your operation. You should avoid using tampons until your next period. Sex and strenuous exercise should be avoided for at least two to four weeks to allow the cervix to heal properly.
Sometimes a cone biopsy can make the cervix slightly weaker, which may increase the risk of miscarriage during pregnancy. In this situation, miscarriage can often be prevented by putting a stitch into the cervix during pregnancy to strengthen it. Your doctor can discuss this with you in more detail if you are concerned about possible future pregnancies. A cone biopsy will not affect your ability to enjoy sex.
The cervix can become very tightly closed after a cone biopsy, although this is extremely rare. This can make it harder for sperm to enter the womb and so can affect the chances of becoming pregnant naturally. If you are still having periods after your cone biopsy, this shows that your cervix is not completely closed.
During the LLETZ| procedure, a wire loop with an electric current (diathermy) is used to remove abnormal areas of tissue. This tissue is then sent to a laboratory to be checked. LLETZ is the most common treatment for CIN.
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