Crizotinib, also known as Xalkori®, is a type of targeted therapy called a tyrosine kinase inhibitor (TKI), also known as a cancer growth inhibitor. Kinases are proteins in the body that regulate how cells grow and divide.
Crizotinib blocks (inhibits) the proteins from sending signals to the cancer to grow. This may help to stop or slow down the cancer.
Crizotinib is used to treat people who have non-small cell lung cancer (NSCLC) and who have a change to certain genes, called ALK or ROS1 genes. If you have this gene change, it is called ALK-positive or ROS positive. Before you start treatment, your doctor will test your cancer cells to see if you have either of these changes in your genes.
Your doctor will talk to you about this treatment and its possible side effects before you agree (consent) to have treatment.