What is small lymphocytic lymphoma (SLL)?

Small lymphocytic lymphoma (SLL) is a type of blood cancer. It is the same as chronic lymphocytic leukaemia (CLL).

SLL and CLL develop when B-cells become abnormal (cancerous). B-cells are white blood cells that normally help fight infection. They are sometimes called B-lymphocytes. Although they have different names, they develop from the same type of B-cell.

Previously, when the abnormal B-cells were mostly in the lymph nodes and spleen, the type of blood cancer was called SLL. When the abnormal B-cells were mostly in the blood and bone marrow, it was called CLL. Most people have abnormal cells in the lymph nodes, spleen, blood and bone marrow. This is why SLL and CLL now considered to be the same condition.

It is more common as people get older. It usually develops slowly. You may not need treatment straightaway.

For healthcare professionals

If you are a healthcare professional, use our guide to find the right information and support for your patients affected by lymphoma. This explains the support available from Macmillan and from other trusted organisations.

Read more

Symptoms, diagnosis and treatment

To find out more, see our information on chronic lymphocytic leukaemia. This explains: 

  • symptoms
  • causes and risk factors
  • diagnosis
  • stages
  • treatment. 

Support for people with small lymphocytic lymphoma (SLL)

We understand that being diagnosed with cancer can affect you both physically and emotionally. We have information and advice to help you.

Talk to someone about small lymphocytic lymphoma (SLL)

Everyone has their own way of dealing with illness and the different emotions they experience. You may find it helpful to talk things over with family and friends or your doctor or nurse.

Macmillan is also here to support you. If you would like to talk, you can:

More information and advice

We know cancer can affect you physically, emotionally and financially. We have information and advice about different ways cancer might impact you, such as help with:

Booklets and resources

Other organisations who offer information and support

The organisations below also offer information and support:

  • Blood Cancer UK

    Blood Cancer UK offers support and information to people affected by blood cancers, including lymphoma.

  • Lymphoma Action

    Lymphoma Action provides high quality information and support for people affected by lymphoma. It provides helpline services and a range of peer support including online support meetings, educational events and webinars. Its website includes TrialsLink, a database of lymphoma clinical trials.

Supporting someone with lymphoma

When someone you know is diagnosed with lymphoma, it can be difficult to know how to support them. You may want information to help you understand what they are going through. Or you may be worried about what to say.

We have information to help with the practical, emotional and financial impacts of supporting someone. You can also talk to us by:

Booklets and resources

Access our SLL information in other formats

We are working to make our website as accessible as possible. We want everyone to be able to use it to find the information they need. We have tips about using settings on your computer or device to help you use our website in our accessibility statement.

We also provide information in a range of languages and formats. If you cannot find the information you are looking for in the format or language you need, email us at cancerinformationteam@macmillan.org.uk

As small lymphocytic lymphoma (SLL) is the same condition as chronic lymphocytic leukaemia (CLL) you may find our resources about CLL helpful.

Order our Understanding chronic lymphocytic leukaemia booklet

It is quick, easy and free to order our booklet Understanding chronic lymphocytic leukaemia (CLL) on be.Macmillan.org.uk

Sign up to create your free be.Macmillan account. Log into your account and choose the booklets you want to order. Complete your order and we will send your items in the post.

Find our chronic lymphocytic leukaemia (CLL) booklet ebook and pdf

If you prefer a pdf, ePub or Mobi version, our Understanding chronic lymphocytic leukaemia (CLL) booklet is available in these formats.

Booklets and resources

More cancer and lymphoma resources

Listen to our non-Hodgkin lymphoma audiobook

You can listen to our Understanding non-Hodgkin lymphoma audiobook. You can also search our full range of audiobooks.

Booklets and resources

Find non-Hodgkin lymphoma information in your language

We have a range of translated cancer information. This includes information about different cancer types, being diagnosed, cancer treatment, and side effects. We have some lymphoma information in the following languages. You can also search our most up to date list of web pages we have translated on request.

If you would like any of our lymphoma information translated into your language, please email cancerinformationteam@macmillan.org.uk

Watch British sign language videos

You can watch our BSL videos about cancer on YouTube.

Find our easy read booklets

Our easy read booklets use simple words and pictures to tell you about cancer. They can be useful if you want information that is easier to understand. 

Looking for large print, Braille or another format?

If you would like our information in a different format such as large print or Braille, email us at cancerinformationteam@macmillan.org.uk or call us free on 0808 808 00 00.

About our information

  • Reviewers

    This information has been written, revised and edited by Macmillan Cancer Support’s Cancer Information Development team. It has been reviewed by expert medical and health professionals and people living with cancer. It has been approved by Senior Medical Editor, Dr Anne Parker, Consultant Haematologist.

    Our cancer information has been awarded the PIF TICK. Created by the Patient Information Forum, this quality mark shows we meet PIF’s 10 criteria for trustworthy health information.

Date reviewed

Reviewed: 01 March 2021
|
Next review: 01 March 2024

This content is currently being reviewed. New information will be coming soon.

Trusted Information Creator - Patient Information Forum
Trusted Information Creator - Patient Information Forum

Our cancer information meets the PIF TICK quality mark.

This means it is easy to use, up-to-date and based on the latest evidence. Learn more about how we produce our information.