Malignant spinal cord compression (MSCC) – symptoms

Malignant spinal cord compression (MSCC) happens when cancer grows in, or near, the spine and presses on the spinal cord and nerves. It is a rare condition, but it is potentially serious. It is important that you know the symptoms so you can get medical advice as soon as possible.

Any type of cancer can spread to the bones of the spine, but MSCC is more common in people with breast, lung or prostate cancers, lymphoma or myeloma.

Symptoms of MSCC include:

  • back or neck pain
  • numbness or pins and needles in your toes, fingers or buttocks
  • feeling unsteady on your feet
  • bladder or bowel problems.

If you notice any of these symptoms, let your doctor know straight away so they can do some tests. The earlier treatment starts, the more likely it is to be effective.

The spinal cord

The spinal cord is a bundle of nerves that runs from the brain down the back. It plays a vital role in many body functions. These include:

  • movement
  • bowel and bladder function
  • the sensations of touch, pain and temperature.

The spinal cord is surrounded by the bones of the spine, which protect it.


What is malignant spinal cord compression (MSCC)?

Malignant spinal cord compression (MSCC) can happen when cancer grows in the bones of the spine or in the tissues around the spinal cord. The cancer can cause pressure (compression) on the spinal cord.

Any type of cancer can spread to the bones of the spine (vertebrae), which may lead to spinal cord compression. But it is more common with certain cancers, including breast, lung and prostate cancer, lymphoma and myeloma.


Signs and symptoms of MSCC

It depends on which part of the spine is affected, but the warning signs could be any one or more of the following.

Unexplained new back or neck pain:

  • The pain may be mild to start with but becomes more severe.
  • It may feel like a ‘band’ around your chest or abdomen.
  • The pain may spread down your leg or arm, or into your lower back and buttocks.
  • Movement may make the pain worse.
  • The pain may get worse when you strain – for example, if you lift something heavy, cough or sneeze.
  • The pain may keep you awake at night.

Numbness or pins and needles in a part of your body such as:

  • your toes
  • your fingers 
  • over the buttocks.

Feeling unsteady on your feet:

  • having difficulty walking
  • leg weakness
  • your legs giving way.

Problems passing urine:

  • you may have difficulty controlling your bladder (incontinence)
  • you may only pass small amounts of urine or none at all.

Constipation or problems controlling your bowels. These symptoms can also be caused by a number of other conditions.

If you have symptoms of MSCC

If you develop any of these symptoms, you should get medical advice immediately. Contact someone straight away, even if it is the weekend or a holiday.

You should contact the hospital team where you usually go for cancer treatment and follow-up appointments. If you are unable to get in touch with anyone, go to the nearest A&E department or contact your GP.

When you speak to a health professional:

  • Describe your symptoms.
  • Tell them you have cancer and are worried you may have spinal cord compression.
  • Tell them that you need to be seen straight away.

Do not wait for further symptoms to develop. The sooner MSCC is diagnosed, the sooner treatment can begin. If left untreated, MSCC will cause permanent problems.


What happens next?

The doctor needs to examine you. If they suspect MSCC, they may tell you to lie flat. The doctor will also arrange an urgent scan of your spine. This is usually an MRI scan, but may be a CT scan if you can’t have an MRI.

The doctor will prescribe some steroids. These help reduce swelling and pressure on the nerves. Tell the doctor if you are diabetic or have had problems with steroids before.

If you have MSCC, the doctor will talk to you about the best treatment options for you. This will depend on the type of cancer you have, which part of the spine is affected and your general health. For the best result, treatment should start as soon as possible. We have more information on the treatment options available.

Back to Other side effects

Avoiding infection

Cancer and its treatments can weaken the immune system. It’s important to try and avoid infection if your immunity is reduced.

Difficulty sleeping

If you are having difficulty sleeping, there are things you can do to help.

Fungating wounds

Fungating wounds are rare. They develop when cancer breaks through the skin and creates a wound.

Chemo brain

Chemo brain describes changes in memory, concentration and the ability to think clearly. These changes can sometimes happen during or after cancer treatment.

Nausea and vomiting

Cancer and its treatment can make you feel sick (nauseous) or be sick (vomit). There are drugs that can help control this.

Peripheral neuropathy

Cancer or its treatment can damage the nerves that are outside the brain and spinal cord. This is called peripheral neuropathy.

Pleural effusion

A pleural effusion is a build-up of fluid in the lining of the lungs. It can be a symptom of cancer.