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<p begin="00:00" end="00:05">[Cat purring]</p>
<p begin="00:06" end="00:08">My name’s Paula Wells and I’m a clinical oncologist,</p>
<p begin="00:08" end="00:12">which means I give radiotherapy and chemotherapy treatments for lung cancer.</p>
<p begin="00:12" end="00:18">Lung cancer is a disease where cells become transformed into what we call malignant or cancerous tissue.</p>
<p begin="00:19" end="00:24">The symptoms are quite hidden, in that they are a cough, which may be a chronic cough</p>
<p begin="00:24" end="00:26">in many of these patients for many years.</p>
<p begin="00:26" end="00:30">What we should notice is that there is a change in their cough pattern. That’s very important.</p>
<p begin="00:31" end="00:34">Other symptoms which would require urgent investigation</p>
<p begin="00:34" end="00:40">are coughing up blood, and that should require immediate referral to a specialist within a hospital setting.</p>
<p begin="00:40" end="00:47">If patients develop persistent or gradual increasing chest pain which is unexplained by other means</p>
<p begin="00:47" end="00:51">or have repeated chest infections requiring multiple courses of antibiotics</p>
<p begin="00:51" end="00:55">or unresolving chest infections, they should also be investigated.</p>
<p begin="00:56" end="01:01">It’s well known that smoking is the major cause of lung cancer,</p>
<p begin="01:01" end="01:06">and this data has been available to us from screening studies performed in the 1950s.</p>
<p begin="01:06" end="01:09">The treatment depends on the type of lung cancer and there are two main groups.</p>
<p begin="01:10" end="01:13">There is small cell lung cancer and non-small cell lung cancer.</p>
<p begin="01:13" end="01:17">If I describe the non-small cell cancer group first,</p>
<p begin="01:17" end="01:23">treatments are related to what we call the stage of the disease, and that defines how advanced the disease is -</p>
<p begin="01:23" end="01:29">whether it’s spread beyond the chest or whether it’s gone into the lymph glands, into the chest, or elsewhere in the body.</p>
<p begin="01:29" end="01:33">If the disease is localised to the chest and it’s technically possible to do an operation</p>
<p begin="01:33" end="01:37">for that patient, then they will be offered a surgical option.</p>
<p begin="01:37" end="01:41">This is the main curative treatment for lung cancer</p>
<p begin="01:41" end="01:47">and is offered in probably up to 20% of cases of lung cancer in the UK.</p>
<p begin="01:48" end="01:55">The second main curative option is radiotherapy, which is giving x-ray treatment, from outside the body,</p>
<p begin="01:55" end="01:58">directed to the lung cancer.</p>
<p begin="01:59" end="02:04">And then the next group of treatments are really what we call palliative or symptom control type treatments</p>
<p begin="02:04" end="02:09">and these include x-ray treatment, or radiotherapy with small numbers of treatments</p>
<p begin="02:09" end="02:15">to help with symptoms such as pain or breathlessness, cough, or bleeding. </p>
<p begin="02:15" end="02:17">and then of course chemotherapy.</p>
<p begin="02:17" end="02:20">The other group of patients is the small cell lung cancer patients.</p>
<p begin="02:20" end="02:23">These behave in a different way. They’re more aggressive.</p>
<p begin="02:23" end="02:27">They’re more likely to spread around in the blood stream at an earlier stage,</p>
<p begin="02:27" end="02:31">so therefore chemotherapy, in the first instance, is the main treatment that we offer</p>
<p begin="02:31" end="02:38">And for those patients that have disease which is localised just to the chest, and have a good response to chemotherapy,</p>
<p begin="02:38" end="02:41">we offer radiotherapy x-ray treatment.</p>
<p begin="02:41" end="02:45">The lung cancer rates are related to smoking exposure,</p>
<p begin="02:45" end="02:51">so historically men have had the highest prevalence of lung cancer and this is still the case,</p>
<p begin="02:51" end="02:54">although, in women this is increasing, unfortunately,</p>
<p begin="02:54" end="03:00">because women are taking up smoking at a higher rate and men are giving up at a higher rate.</p>
<p begin="03:00" end="03:03">And also, women are starting at an earlier age.</p>
<p begin="03:03" end="03:07">It’s clear that the main thing that one can do to reduce your risk of lung cancer is</p>
<p begin="03:07" end="03:13">either give up smoking if you are a smoker and try to avoid taking up smoking if you are a non-smoker.</p>
<p begin="03:14" end="03:17">A good diet full of fresh fruit and vegetables</p>
<p begin="03:17" end="03:22">and a good exercise regime and a general healthy lifestyle</p>
<p begin="03:22" end="03:24">can help improve your outcomes from cancers</p>
<p begin="03:24" end="03:30">because we know that those people who have poor general health do less well with any treatment.</p>
<p begin="03:31" end="03:35">It’s certainly true to say that with the changes in practices that have occurred</p>
<p begin="03:35" end="03:41">over the last five or ten years with regard to the improvement in the diagnostic pathway for patients</p> 
<p begin="03:41" end="03:43">and the availability of all treatment options,</p>
<p begin="03:44" end="03:47">that the outcomes for lung cancer are improving.</p>
<p begin="03:47" end="03:54">And there is no doubt that if patients present earlier that the results for lung cancer patients will be improved.</p>
<p begin="03:55" end="04:05"> For information, help, or if you just want to chat, call the Macmillan Support Line on 0808 808 00 00, or visit 

Macmillan.org.uk</p>
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