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<p begin="00:05" end="00:11">My name is Karen Harrison-Phipps, I'm one of the consultant thoracic surgeons here at Guy's Hospital.</p>
<p begin="00:11" end="00:17">Guy's Hospital is part of the Guy's and St. Thomas' Foundation Trust, and one of the biggest teaching hospitals in London.</p>
<p begin="00:18" end="00:29">The gullet is a food tube that connects the mouth and the stomach, and it passes through the chest, between the lungs,</p>
<p begin="00:29" end="00:32">in what we call the 'mediastinum' which means 'the middle of the chest'.</p> 
<p begin="00:32" end="00:37">The symptoms of gullet cancer are difficulty with eating</p>
<p begin="00:31" end="00:40">and that is known as dysphagia.</p>
<p begin="00:40" end="00:44">In addition, patients, because they find it difficult to eat, lose weight.</p>
<p begin="00:44" end="00:48">Those are the two most common symptoms, weight loss and a difficulty with eating. </p>
<p begin="00:48" end="00:53">Patients who do report weight loss with eating difficulty</p>
<p begin="00:52" end="00:59">would definitely be referred to a unit that specialises in diagnosing these problems,</p>
<p begin="00:59" end="01:06">and some of the tests would include just simple x-rays and perhaps more detailed x-rays in the form of CT scans.</p>
<p begin="01:06" end="01:16">But probably the most important test is an endoscopy test, which is a camera test where a small camera is passed down the gullet</p>
<p begin="01:16" end="01:22">this allows a very thorough inspection of the insides of the gullet but it also allows the operator to take a piece</p>
<p begin="01:22" end="01:28">or a biopsy away that is often very helpful in getting a diagnosis of gullet cancer.</p>
<p begin="01:28" end="01:36">The treatment options for gullet cancer are quite varied and there is a treatment option for every patient.</p>
<p begin="01:36" end="01:43">It just depends on their stage of cancer, and it depends on their fitness as a patient as well, so every patient is individual.</p>
<p begin="01:43" end="01:50">But broadly, the treatment options for gullet cancer would include surgery, chemotherapy and radiotherapy.</p>
<p begin="01:51" end="01:55">Where we can, we like to offer surgery, because often this gives the best chance of a cure,</p>
<p begin="01:55" end="02:03">and an operation to remove a gullet cancer is called an oesophagectomy. </p>
<p begin="02:03" end="02:11">It's quite a big operation, but now, with these operations being centred in large expert centres, </p>
<p begin="02:11" end="02:15">the results and the outlook can be quite promising.</p>
<p begin="02:15" end="02:22">When an operation is not possible for patients with gullet cancer there still are many treatment options.</p>
<p begin="02:22" end="02:27">These would include chemotherapy and radiotherapy, </p>
<p begin="02:27" end="02:32">but also a number of other treatments that may perhaps help the patient to swallow better.</p>
<p begin="02:32" end="02:39">Chemotherapy and radiotherapy in shrinking the tumour, can also gain good local control of the tumour, </p>
<p begin="02:39" end="02:44">and may prevent or reduce local spread of the tumour.</p>
<p begin="02:45" end="02:50">Sadly, gullet cancer, or oesophegeal cancer, is on the increase, especially in western societies.</p>
<p begin="02:50" end="02:56">This is down to the effects of increased alcohol consumption, a high incidence of smoking, </p>
<p begin="02:56" end="03:01">and perhaps increased alcohol leading to weight gain,</p>
<p begin="03:01" end="03:07">and the prescence of reflux, which means acid refluxing out of your stomach into the gullet.</p>
<p begin="03:07" end="03:11">All of these factors are thought to account for the increase in cancer of the gullet.</p>
<p begin="03:11" end="03:19">If, unfortunately, it is found that you do have cancer of the gullet, there are centres in the United Kingdom,</p> 
<p begin="03:19" end="03:23">of excellence that provide top class treatment for cancer of the gullet, </p>
<p begin="03:23" end="03:27">including surgery, chemotherapy, and radiotherapy</p>
<p begin="03:27" end="03:30">and results are improving all the time.</p>
<p begin="03:32" end="03:44">[New speaker] For information, help, or if you just want a chat, call the Macmillan Support Line on 0808 808 0000 or visit macmillan.org.uk</p>
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