Staging of myeloma
The stage of a cancer is a term used to describe its extent and how much it’s affecting the body.
Knowing the stage of the myeloma helps doctors plan the most appropriate treatment for you. Generally, myeloma is divided into three stages, which indicate the effect the disease is having on the body and how quickly or slowly it may develop.
A commonly used staging system for myeloma is the International Staging System (ISS). This system looks at the levels of the blood proteins beta-2 microglobulin and albumin.
The beta-2 microglobulin level is less than 3.5 milligrams per deciliter (3.5mg/dL) and the albumin level is greater than or equal to 3.5g/dL. This is early-stage myeloma.
Neither stage 1 or 3. This is intermediate-stage myeloma.
The beta-2 microglobulin level is greater than or equal to 5.5 mg/dL. This is advanced myeloma.